Daan Hein Alsem

Dr. Alsem is the Director of Research and Engineering at Hummingbird Scientific. He has two decades worth of research and development experience with in-situ and analytical transmission electron microscopy, electron microscopy-centered experimentation, and microscopy methods and hardware development.

After acquiring his Ph.D. at UC Berkeley, Dr. Alsem worked at the Lawrence Berkeley National Laboratory’s National Center of Electron Microscopy. He previously also held an Affiliate Assistant Professor position in the Department of Mechanical Engineering at the University of Washington.

Learn more about his research interests and publications from his Google Scholar profile or by connecting to his LinkedIn profile below:

Selected Publications

Liquid thickness estimation in transmission electron microscopy

Lau Morten Kaas, Raquel Aymerich-Armengol, Daan Hein Alsem, Christian Danvad Damsgaard, Stig Helveg, Jakob Kibsgaard, Peter Christian Kjærgaard Vesborg

Ultramicroscopy

2026

Lau Morten Kaas, Raquel Aymerich-Armengol, Daan Hein Alsem, Christian Danvad Damsgaard, Stig Helveg, Jakob Kibsgaard, Peter Christian Kjærgaard Vesborg. “Liquid thickness estimation in transmission electron microscopy”. Ultramicroscopy (2026)

Strain-associated nanoscale fluctuating lithium transport within single-crystalline LiNi1/3Mn1/3Co1/3O2 cathode particles

Danwon Lee, Chihyun Nam, Juwon Kim, Sooseong Hwang, Bonho Koo, Hyejeong Hyun, Jinkyu Chung, Sungjae Seo, Munsoo Song, Jaejung Song, Myeongjun Kim, Daan Hein Alsem, Norman J. Salmon, Suyong Lee, Yeonchoo Cho, Namdong Kim, David A. Shapiro, Jongwoo Lim

Nature Communications

2025

Danwon Lee, Chihyun Nam, Juwon Kim, Sooseong Hwang, Bonho Koo, Hyejeong Hyun, Jinkyu Chung, Sungjae Seo, Munsoo Song, Jaejung Song, Myeongjun Kim, Daan Hein Alsem, Norman J. Salmon, Suyong Lee, Yeonchoo Cho, Namdong Kim, David A. Shapiro, Jongwoo Lim. “Strain-associated nanoscale fluctuating lithium transport within single-crystalline LiNi1/3Mn1/3Co1/3O2 cathode particles”. Nature Communications (2025)

Revealing the mechanisms of non-thermal plasma-enabled iron oxide reduction through nanoscale operando TEM

Jae Hyun Nam, K. Andre Mkhoyan, Daan Hein Alsem, Peter J. Bruggeman

Nature Communications

2025

Jae Hyun Nam, K. Andre Mkhoyan, Daan Hein Alsem, Peter J. Bruggeman. “Revealing the mechanisms of non-thermal plasma-enabled iron oxide reduction through nanoscale operando TEM”. Nature Communications (2025)

Nanometer-scale resolution in an ultra-high pressure environmental TEM holder

George G. Hollyer, Dmitri N. Zakharov, Daan Hein Alsem, Calvin Parkin, Eric A. Stach

MRS Communications

2025

George G. Hollyer, Dmitri N. Zakharov, Daan Hein Alsem, Calvin Parkin, Eric A. Stach. “Nanometer-scale resolution in an ultra-high pressure environmental TEM holder”. MRS Communications (2025)

(Battery Student Slam 8 Award Winner) Multi-Clustered Lithium Diffusion in Single-Crystalline NMC Battery Particles

Danwon Lee, Chihyun Nam, Juwon Kim, Bonho Koo, Hyejeong Hyun, Jinkyu Chung, Sungjae Seo, Munsoo Song, Jaejung Song, Daan Alsem, Norman Salmon, Suyong Lee, Namdong Kim, David Shapiro, Jongwoo Lim

ECS Meeting Abstracts

2024

Danwon Lee, Chihyun Nam, Juwon Kim, Bonho Koo, Hyejeong Hyun, Jinkyu Chung, Sungjae Seo, Munsoo Song, Jaejung Song, Daan Alsem, Norman Salmon, Suyong Lee, Namdong Kim, David Shapiro, Jongwoo Lim. “(Battery Student Slam 8 Award Winner) Multi-Clustered Lithium Diffusion in Single-Crystalline NMC Battery Particles”. ECS Meeting Abstracts (2024)

Spatiotemporal active phase evolution for CO2 electrocatalysis

Juwon Kim, Si Young Lee, Se-Jun Kim, Bonho Koo, Jinkyu Chung, Danwon Lee, Subin Choi, Jimin Kim, Sungjae Seo, Chihyun Nam, Karl Adrian Gandionco, Gwangsu Bak, Sugeun Jo, Namdong Kim, Hyun-Joon Shin, Keun Hwa Chae, Da Hye Won, Matthew A. Marcus, David A. Shapiro, Shu-Chih Haw, Daan Hein Alsem, Norman J. Salmon, Byoung Koun Min, Hyungjun Kim, Yun Jeong Hwang, Jongwoo Lim

Joule

2024

Juwon Kim, Si Young Lee, Se-Jun Kim, Bonho Koo, Jinkyu Chung, Danwon Lee, Subin Choi, Jimin Kim, Sungjae Seo, Chihyun Nam, Karl Adrian Gandionco, Gwangsu Bak, Sugeun Jo, Namdong Kim, Hyun-Joon Shin, Keun Hwa Chae, Da Hye Won, Matthew A. Marcus, David A. Shapiro, Shu-Chih Haw, Daan Hein Alsem, Norman J. Salmon, Byoung Koun Min, Hyungjun Kim, Yun Jeong Hwang, Jongwoo Lim. “Spatiotemporal active phase evolution for CO2 electrocatalysis”. Joule (2024)

Nanoscopic Strain-Associated Lithium Diffusion in Single-Crystalline NMC Battery Particles

Danwon Lee, Chihyun Nam, Juwon Kim, Bonho Koo, Hyejeong Hyun, Jinkyu Chung, Sungjae Seo, Munsoo Song, Jaejung Song, Daan Hein Alsem, Norman Salmon, Suyong Lee, Namdong Kim, David Shapiro, Jongwoo Lim

ECS Meeting Abstracts

2024

Danwon Lee, Chihyun Nam, Juwon Kim, Bonho Koo, Hyejeong Hyun, Jinkyu Chung, Sungjae Seo, Munsoo Song, Jaejung Song, Daan Hein Alsem, Norman Salmon, Suyong Lee, Namdong Kim, David Shapiro, Jongwoo Lim. “Nanoscopic Strain-Associated Lithium Diffusion in Single-Crystalline NMC Battery Particles”. ECS Meeting Abstracts (2024)

In-Situ Liquid-Electrochemical X-Ray and Electron Microscopy for Multi-Modal Energy Materials Characterization

Calvin Parkin, Tyler Mefford, Jongwoo Lim, Aram Yoon, Rui Serra-Maia, Pawan Kumar, See Wee Chee, William C. Chueh, Daan Hein Alsem, Norman Salmon, Eric A. Stach

ECS Meeting Abstracts

2024

Calvin Parkin, Tyler Mefford, Jongwoo Lim, Aram Yoon, Rui Serra-Maia, Pawan Kumar, See Wee Chee, William C. Chueh, Daan Hein Alsem, Norman Salmon, Eric A. Stach. “In-Situ Liquid-Electrochemical X-Ray and Electron Microscopy for Multi-Modal Energy Materials Characterization”. ECS Meeting Abstracts (2024)

Correlative operando microscopy of oxygen evolution electrocatalysts

J. Tyler Mefford, Andrew R. Akbashev, Minkyung Kang, Cameron L. Bentley, William E. Gent, Haitao D. Deng, Daan Hein Alsem, Young-Sang Yu, Norman J. Salmon, David A. Shapiro, Patrick R. Unwin, William C. Chueh

Nature

2021

J. Tyler Mefford, Andrew R. Akbashev, Minkyung Kang, Cameron L. Bentley, William E. Gent, Haitao D. Deng, Daan Hein Alsem, Young-Sang Yu, Norman J. Salmon, David A. Shapiro, Patrick R. Unwin, William C. Chueh. “Correlative operando microscopy of oxygen evolution electrocatalysts”. Nature (2021)

Dynamic Imaging of Nanostructures in an Electrolyte with a Scanning Electron Microscope

Aram Yoon, Antonia Herzog, Philipp Grosse, Daan Hein Alsem, See Wee Chee, Beatriz Roldán Cuenya

Microscopy and Microanalysis

2021

Aram Yoon, Antonia Herzog, Philipp Grosse, Daan Hein Alsem, See Wee Chee, Beatriz Roldán Cuenya. “Dynamic Imaging of Nanostructures in an Electrolyte with a Scanning Electron Microscope”. Microscopy and Microanalysis (2021)

Cryo-Electrical Microscopy for Quantum and Advanced Energy Applications

Khim Karki, Daan Hein Alsem, Norman Salmon

Microscopy and Microanalysis

2021

Khim Karki, Daan Hein Alsem, Norman Salmon. “Cryo-Electrical Microscopy for Quantum and Advanced Energy Applications”. Microscopy and Microanalysis (2021)

Using In-Situ TEM to Investigate the Role of Lithium Iodide Addition to Lithium Thiophosphate

Nikhilendra Singh, James Horwath, Timothy Arthur, Daan Hein Alsem; Marm Dixit, Pavel Shevchenko, Michael Jones, Kelsey Hatzell, Eric Stach

Microscopy and Microanalysis

2021

Nikhilendra Singh, James Horwath, Timothy Arthur, Daan Hein Alsem, Marm Dixit, Pavel Shevchenko, Michael Jones, Kelsey Hatzell, Eric Stach. “Using In-Situ TEM to Investigate the Role of Lithium Iodide Addition to Lithium Thiophosphate”. Microscopy and Microanalysis (2021)

In Situ Transmission Electron Microscopy Measurements of Ge Nanowire Synthesis with Liquid Metal Nanodroplets in Water

Quintin Cheek, Eli Fahrenkrug, Sofiya Hlynchuk, Daan Hein Alsem, Norman J. Salmon, Stephen Maldonado

ACS Nano

2020

Quintin Cheek, Eli Fahrenkrug, Sofiya Hlynchuk, Daan Hein Alsem, Norman J. Salmon, Stephen Maldonado. “In Situ Transmission Electron Microscopy Measurements of Ge Nanowire Synthesis with Liquid Metal Nanodroplets in Water”. ACS Nano (2020)

Realistic Bulk Electrochemistry in Liquid Cell Microscopy

Khim Karki, Rui Serra-Maia, Eric Stach, Daan Hein Alsem, Norman Salmon

Microscopy and Microanalysis

2020

Khim Karki, Rui Serra-Maia, Eric Stach, Daan Hein Alsem, Norman Salmon. “Realistic Bulk Electrochemistry in Liquid Cell Microscopy”. Microscopy and Microanalysis (2020)

In situ operando Study of Photoelectrochemistry Using Optical Liquid Cell Microscopy

Khim Karki, Pawan Kumar, Antoine Verret, Noah Glachman, Daan Hein Alsem, Deep Jariwala, Norman Salmon, Eric Stach

Microscopy and Microanalysis

2020

Khim Karki, Pawan Kumar, Antoine Verret, Noah Glachman, Daan Hein Alsem, Deep Jariwala, Norman Salmon, Eric Stach. “In situ operando Study of Photoelectrochemistry Using Optical Liquid Cell Microscopy”. Microscopy and Microanalysis (2020)

Focused Ion Beam Sample Preparation for High Temperature In-situ Transmission Electron Microscopy Experiments: Use Carbon for Now

Jules Gardener, Austin Akey, Daan Hein Alsem, David Bell

Microscopy and Microanalysis

2020

Jules Gardener, Austin Akey, Daan Hein Alsem, David Bell. “Focused Ion Beam Sample Preparation for High Temperature In-situ Transmission Electron Microscopy Experiments: Use Carbon for Now”. Microscopy and Microanalysis (2020)

Non-equilibrium Structural Phase Transformations in Atomically Thin Transition Metal Dichalcogenides

Pawan Kumar, James Horwath, Alexandre Foucher, Chrisopher Price, Natalia Acero, Vivek Shenoy, Deep Jariwala, Eric Stach, Daan Hein Alsem

Microscopy and Microanalysis

2020

Pawan Kumar, James Horwath, Alexandre Foucher, Chrisopher Price, Natalia Acero, Vivek Shenoy, Deep Jariwala, Eric Stach, Daan Hein Alsem. “Non-equilibrium Structural Phase Transformations in Atomically Thin Transition Metal Dichalcogenides”. Microscopy and Microanalysis (2020)

Understanding the Relationship Between Air Exposure, Electron Dose and Beam Damage in Solid Electrolyte Materails

Eric Stach, James Horwath, Nikhilendra Singh, Timothy Arthur, Daan Hein Alsem, Norman Salmon

Microscopy and Microanalysis

2020

Eric Stach, James Horwath, Nikhilendra Singh, Timothy Arthur, Daan Hein Alsem, Norman Salmon. “Understanding the Relationship Between Air Exposure, Electron Dose and Beam Damage in Solid Electrolyte Materails”. Microscopy and Microanalysis (2020)

Using Operando Electrochemical TEM as Part of a Correlative Approach to Characterize Failure Modes in Solid-state Energy Storage Devices

Nikhilendra Singh, James Horwath, Timothy Arthur, Daan Hein Alsem, Eric Stach

Microscopy and Microanalysis

2020

Nikhilendra Singh, James Horwath, Timothy Arthur, Daan Hein Alsem, Eric Stach. “Using Operando Electrochemical TEM as Part of a Correlative Approach to Characterize Failure Modes in Solid-state Energy Storage Devices”. Microscopy and Microanalysis (2020)

Operando Electrochemical TEM of Solid-State Energy Storage Materials Using a Probe-Based Biasing Holder

Nikhilendra Singh, James Horwath, Alexandre Foucher, Timothy S. Arthur, Julio A. Rodríguez Manzo, Daan Hein Alsem, Eric Stach

Microscopy and Microanalysis

2019

Nikhilendra Singh, James Horwath, Alexandre Foucher, Timothy S. Arthur, Julio A. Rodríguez Manzo, Daan Hein Alsem, Eric Stach. “Operando Electrochemical TEM of Solid-State Energy Storage Materials Using a Probe-Based Biasing Holder”. Microscopy and Microanalysis (2019)