Key publications, open-source tools, and research directions in TEM automation, 4D-STEM, tomography, and AI-assisted microscopy.

Software is now central to modern transmission electron microscopy. Today’s TEM and STEM workflows depend on automated acquisition, microscope scripting, detector synchronization, tomography reconstruction, 4D-STEM analysis, machine learning, and increasingly autonomous experimental control.

This publication library curates influential papers, software platforms, and research directions that have shaped the software ecosystem for modern electron microscopy.

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Data Analysis Software
10.1007/978-1-4757-3205-4_14
SEM
Strategies for Analyzing EBSD Datasets
Wayne E. King, James S. Stölken, Mukul Kumar, Adam J. Schwartz
Electron Backscatter Diffraction in Materials Science
2000

The authors discuss practical strategies for analyzing EBSD datasets. The chapter covers interpretation techniques and data-processing methods used in crystallographic characterization.

Simulation Software
10.1109/NNSP.2000.890144
TEM
Two dimensional phase retrieval using neural networks
A. Burian, P. Kuosmanen, J. Saarinen, C. Rusu
Neural Networks for Signal Processing X. Proceedings of the 2000 IEEE Signal Processing Society Workshop (Cat. No.00TH8501)
2000

This study explores neural network methods for two-dimensional phase retrieval problems. The proposed approach reconstructs phase information from measured data while reducing computational complexity.

Open-Source TEM Software
10.1002/(SICI)1097-4539(199909/10)28:5<320::AID-XRS359>3.0.CO;2-1
X-ray
Synchrotron radiation X-Ray fluorescence at the LNLS: beamline instrumentation and experiments
Carlos A. Pérez, Martin Radtke, Héctor J. Sánchez, Helio Tolentino, Regis T. Neuenshwander, William Barg, Marcelo Rubio, María Izabel Silveira Bueno, Ivo M. Raimundo, Jarbas J. R. Rohwedder
X-Ray Spectrometry
1999

This work describes beamline instrumentation and experimental applications of synchrotron-radiation X-ray fluorescence at LNLS. The setup supports detailed elemental analysis across diverse research fields.

Data Analysis Software
10.2172/771196
X-ray
Analysis of neutron scattering data: Visualization and parameter estimation
J.J. Beauchamp, V. Fedorov, W.A. Hamilton, M. Yethiraj
1998

This work discusses methods for visualization and parameter estimation in neutron scattering data analysis. The techniques support interpretation of experimental results and extraction of physical insights.

Data Analysis Software
10.1080/00222349808220494
X-ray
Micro x-ray small-angle scattering with synchrotron radiation
C. Riekel, P. Engström, C. Martin
Journal of Macromolecular Science, Part B
1998

The authors examine micro-scale small-angle X-ray scattering experiments performed with synchrotron radiation. The technique supports structural investigations of polymers, biological samples, and complex materials.

Tomography Software
10.1016/S0168-583X(97)00994-4
X-ray
Synchrotron energy-dispersive X-ray diffraction tomography
C. Hall, P. Barnes, J.K. Cockcroft, S.L. Colston, D. Häusermann, S.D.M. Jacques, A.C. Jupe, M. Kunz
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
1998

This article examines synchrotron energy-dispersive X-ray diffraction tomography for spatially resolved materials characterization. The technique combines diffraction and tomographic imaging to reveal internal structural information.

Open-Source TEM Software
10.1007/1-4020-4496-8_312
X-ray
Synchrotron X-ray fluorescence analysis
Philip J. Potts
Geochemistry
1998

This chapter reviews synchrotron X-ray fluorescence analysis as a powerful tool for elemental characterization. High sensitivity and multi-element detection capabilities support a wide range of scientific applications.

Data Analysis Software
10.1007/978-3-7091-7506-4_6
TEM
Thin Film Analysis and Chemical Mapping in the Analytical Electron Microscope
David B. Williams, Masashi Watanabe, Derrick T. Carpenter
Modern Developments and Applications in Microbeam Analysis
1998

The authors review analytical electron microscopy methods for thin-film analysis and chemical mapping. The techniques enable spatially resolved characterization of composition, interfaces, and microstructural features.

Data Analysis Software
10.1080/00150199708015629
TEM
Atomic resolution imaging of ferroelectric domains
L. A. Bursill
Ferroelectrics
1997

This study demonstrates atomic-resolution imaging techniques for investigating ferroelectric domain structures. The observations provide direct insight into polarization behavior and nanoscale domain configurations.

Open-Source TEM Software
10.1016/S0921-4526(97)00865-X
X-ray
NeXus: A common format for the exchange of neutron and synchroton data
P Klosowski, M Koennecke, J.Z Tischler, R Osborn
Physica B: Condensed Matter
1997

The authors present NeXus as a common data format for exchanging neutron and synchrotron experimental data. Standardization improves interoperability, data sharing, and long-term usability across facilities.

Data Analysis Software
10.1006/jsbi.1996.0013
TEM
Computer Visualization of Three-Dimensional Image Data Using IMOD
James R. Kremer, David N. Mastronarde, J.Richard McIntosh
Journal of Structural Biology
1996

IMOD presents a comprehensive environment for visualizing and modelling three-dimensional microscopy datasets. The software enables interactive exploration, segmentation, and interpretation of volumetric image information.

Data Analysis Software
10.4028/www.scientific.net/MSF.207-209.13
SEM
Orientation Imaging Microscopy: Applications to the Characterization of the Grain-Boundary Network
Brent L. Adams
Materials Science Forum
1996

This article reviews orientation imaging microscopy applications for characterizing grain-boundary networks. The approach provides quantitative insight into microstructure, texture, and material behavior.

Simulation Software
10.1016/0968-4328(96)00024-8
TEM
The Intensity of Elastic and Inelastic Multiple Scattering in EELS
S.C. Cheng, Y.Y. Wang, V.P. Dravid
Micron
1996

This study analyzes the contributions of elastic and inelastic multiple scattering in EELS measurements. The results improve understanding of signal formation and quantitative spectral interpretation.

Data Analysis Software
10.1063/1.1145755
X-ray
Efficient extraction window for high-throughput x-ray lithography beamlines
Kenichi Kuroda, Takashi Kaneko, Seiichi Itabashi
Review of Scientific Instruments
1995

This work investigates efficient extraction-window designs for high-throughput synchrotron X-ray lithography beamlines. The proposed configuration enhances operational performance and reliability.

In-Situ TEM Software
10.1016/0921-5093(95)09936-0
TEM
In situ TEM sintering of nano-sized ZrO2 particles
J. Rankin, B.W. Sheldon
Materials Science and Engineering: A
1995

This paper investigates the sintering behavior of nanoscale zirconia particles through in-situ TEM observations. Real-time imaging reveals grain growth, densification, and microstructural evolution during heating.

Simulation Software
10.1080/00150199508221841
TEM
Using symmetry in frozen phonon calculations
Harold T. Stokes
Ferroelectrics
1995

This work demonstrates how symmetry considerations can reduce computational effort in frozen phonon simulations. The strategy accelerates calculations while preserving accuracy in electron scattering studies.

Data Analysis Software
10.2172/203215
X-ray
Experimental Physics and Industrial Control System (EPICS): Application source/release control for EPICS R3.11.6
B. Zieman, M. Kraimer
1994

This work describes source and release control practices for EPICS applications. The framework supports reliable management of software used in experimental physics and industrial control systems.

Open-Source TEM Software
10.1557/PROC-375-275
X-ray
High Resolution Synchrotron X-Ray Diffraction Tomography of Polycrystalline Samples
S. R. Stock, A. Guvenilir, D. P. Piotrowski, Z. U. Rek
MRS Proceedings
1994

The study presents high-resolution synchrotron X-ray diffraction tomography of polycrystalline materials. The method enables non-destructive three-dimensional characterization of strain and microstructural features.

In-Situ TEM Software
10.1557/PROC-364-219
TEM
Phase Transformations in the Fe-Al System Studied by “In-Situ” Tem Heating
A. Korner
MRS Proceedings
1994

This paper investigates phase transformations in Fe-Al alloys through in-situ TEM heating experiments. The observations track domain evolution and antiphase boundary behavior during thermal processing.

Tomography Software
10.1557/PROC-348-235
X-ray
Time-Resolved Spectroscopy of Scintillation Materials using X-RAY Synchrotron Radiation
Andrey N. Belsky, Vitaly V. Mikhaihin, Andrey L. Rogalev, Eduard I. Zinin
MRS Proceedings
1994

This work investigates time-resolved spectroscopy of scintillation materials using synchrotron X-ray radiation. Measurements of luminescence spectra and decay kinetics provide insight into scintillator performance.

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